George Fritsma

MS, MLS, Lab Scientist, Educator, Author

George Fritsma is a medical laboratory scientist, educator, and author. George contributed five chapters to Keohane EM, Butina MM, Mirza KM, Walenga JM: Rodak’s Hematology; Clinical Principles and Applications, Seventh Edition, 2025, Elsevier; and is the co-author of Bennett A, Fritsma GA, Ernst DJ: Quick Guide to Blood Collection Edition 2, 2016, Marques MB, Fritsma GA: Quick Guide to Coagulation Testing Edition 3, 2015, and Reddy V, Marques MB, Fritsma GA: Quick Guide to Hematology Testing Edition 2, 2013, along with three additional titles, all published by AACC Press. He is a consultant in the Laboratory Medicine Department of Pathology at the University of Alabama at Birmingham. George is a member of the International Society on Thrombosis and Hemostasis, the International Society for Laboratory Hematology, and the American Society for Clinical Laboratory Science.

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November 2026 QQ: Antifibrinolytic

Our November QQ asks: “Which is an antifibrinolytic used to control bleeding?” Antifibrinolytics are part of a series of therapeutics used to control hemorrhage in acquired or congenital bleeding disorders or in preparation for potentially bloody surgeries. The key reference for this question is Murphy MC, Klein HG. Blood Component and Pharmacologic Therapy for Hemostatic […]

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Quick Question Archive

CanVECTOR and Thrombosis Canada Conferences November 7

Thrombosis Unpacked: Decisions That Matter November 7, 2026 Join healthcare professionals from across Canada in Montreal for two days of practical, multidisciplinary education focused on difficult thrombosis and anticoagulation decisions encountered in real-world clinical care. The 2026 CanVECTOR and Thrombosis Canada Conferences bring together clinicians, researchers, pharmacists, nurses, and healthcare professionals to explore evolving evidence, controversial […]

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Events

Platelets in Children

Check with your local medical library for this review on pediatric platelet development: Letunica N, Monagle P, Attard C. Platelets in children: physiological function, developmental regulation, and clinical significance in disease states. Semin Thromb Hemost. 2026. doi: 10.1055/a-2907-8906. PMID: 42442705. Abstract Platelets play a fundamental role in hemostasis; however, their phenotype, reactivity, and function vary […]

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Platelet Function Testing

Clinical Anticoagulant Measurement

Check your local medical library for these anticoagulation measurement reviews published in the November 2026 issue of Seminars in Thrombosis and Hemostasis: Favaloro EJ, Reardon B, Pasalic L. Laboratory monitoring and measuring of clinical anticoagulants. Semin Thromb Hemost. 2026;52(8):927–36. doi: 10.1055/a-2907-8841. PMID: 42442704. Abstract Haemostasis reflects a balance between procoagulant and anticoagulant forces. A relative […]

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Anticoagulant Therapy

November 2026 Cheat Sheet

Hello, click below for your November 2026 Cheat Sheet. If you would like a push copy with links to our recent posts, please complete the application form on the right. Fritsma Factor is hosted by our family of hemostasis diagnostics providers, Precision BioLogic, Affinity Biologicals, and George King Bio-Medical, and our informational services are gratis. […]

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Cheat Sheets

October 2026 QQ: Anti-Phospholipid Antibody Summary

Our October 2026 quiz, with 32 respondents, asked, “Which is NOT an antiphospholipid antibody?” The answers reveal participants’ wisdom: Anti beta-2 glycoprotein 1: 1 (3%) Alpha-2 antiplasmin: 23 (72%) Lupus anticoagulant: 1 (3%) Antiprothrombin: 7 (22%) Anticardiolipin: 0 The only mislead that attracted respondents was antiprothrombin, a relatively rare APL that is associated with bleeding. […]

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Quick Question Archive

Should We Publish Measurement Uncertainty Data?

Check with your medical library for MacDonald S. Measurement uncertainty in the hemostasis laboratory. Semin Thromb Hemost. 2026;52(8):899-907. doi: 10.1055/a-2723-9166. PMID: 41109209. Abstract Clinical laboratory results are inherently uncertain. Variability arises when repeating measurements of the same sample under different conditions. Measurement uncertainty (MU) is a metrological framework that quantifies this variability, enabling clinical interpretation […]

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Validation

Historical Review Describing Hemorrhage and Thrombosis

Check with your local medical library for Franchini M, Zani M, Focosi D. Human evolution: between hemorrhage and thrombosis. Semin Thromb Hemost. 2026. doi: 10.1055/a-2905-4308. PMID: 42398954. Abstract The human coagulation system has resulted from thousands of years of evolutionary pressure, finely balancing the competing risks of lethal hemorrhage and catastrophic thrombosis. There are several […]

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Bleeding Disorders

Illustrated Review: History of Anticoagulant Pharmacology

Here’s an open-access illustrated review that includes FXI and FXII inhibitors currently in development: Wichaiyo S. Pharmacology of anticoagulants: from heparin to novel target-specific agents. J Thromb Haemost. 2026:S1538-7836(26)00486-1. doi: 10.1016/j.jtha.2026.08.001. PMID: 42567362. Abstract Anticoagulants are the drugs of choice for the management of various thromboembolic disorders affecting both arteries and veins. This review delineates […]

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Anticoagulant Therapy

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