The CHA2DS2-VASc score assigns points to a series of clinical observations in patients with non-valvular atrial fibrillation (AFIB ). CHA2DS2-VASc scores are used to predict the risk of ischemic stroke.
The score is computed as follows:
- Congestive heart failure or left ventricular systolic dysfunction: 1 point
- Hypertension: BP consistently above 140/90 mmHg or treated hypertension on medication: 1 point
- Age ≥75 years: 2 points
- Diabetes mellitus: 1 point
- Stroke, VTE , TIA : 2 points
- Vascular disease; PAD , MI, aortic plaque: 1 point
- Age 65–74: 1 point
- Sex category, female: 1 point
The CHA2DS2-VASc score translates to stroke risk as follows...
6 and 7: 9.8%
Stroke rates vary by study setting, population, and demographic and therapeutic efficacy varies by clinical trial design, but In general, a stroke risk of 2% or over dictates anticoagulant therapy according to international guidelines.
Nielsen PB, Larsen TB, Skjøth F, Overvad TF , Lip GYH. Stroke and thromboembolic event rates in atrial fibrillation according to different guideline treatment thresholds: A nationwide cohort study. Scientific Reports 2016;6: 27410. Bibcode:2016NatSR...627410N. doi:10.1038/srep27410. PMC 4893655. PMID 27265586