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STAT Lupus Testing?

From Ben Troyer at Med Central Health System:  Should lupus anticoagulant testing be offered on a STAT basis? Our LA test volume is pretty low—we average 3–5 requests per week. We make the test available as a STAT, but I’m not sure that this is necessary or appropriate. I’d appreciate any input. Thanks!

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Whole Blood Platelet Aggregometry

From Rob Hillmanwhat is the purpose of diluting blood with saline when running impedance aggregometry?

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Ristocetin Cofactor Assay

From Kelly Townsend: Is anyone using the BioData PAP-8e for ristocetin cofactor (RICO) testing? We’ve moved from the old PAP-4 to the newer version, but are struggling with the assay. We’d appreciate being able to correspond with anyone who is sucessfully running RICO on the PAP-8e.

Mayo Conference Sept 10–12

You are invited to the Clinical and Laboratory Update in Thrombosis, Anticoagulation and Vascular Medicine: A Board Review Primer, this fall’s Mayo School of Continuous Professional Development at the Mayo Civic Center, Rochester, Minnesota. This is a new location for the meeting, and you will find both The Fritsma Factor and Precision BioLogic represented in the exhibit. This is one of the iconic hemostasis meetings of the year, and we hope to see you there.

Back to the ELT

In follow-up to Cassandra McGeachy’s August 7 question on the euglobulin lysis time (ELT), I’ve found two references for upgraded ELT methods that may be helpful.They are:

  • Cellai AP. Lami D, Magi A, et al. Assessment of fibrinolytic activity by measuring the lysis time of a tissue factor-induced clot: a feasibility evaluation. Clin Appl Thromb Hemost 2010;16:337–44.
  • Smith AA, Jacobson LJ, Miller BI, et al. A new euglobulin clot lysis assay for global fibrinolysis. Thrombos Research 2003:112:329–37.

Honolulu Oct 21–22

George presents “Monitoring the New Anticoagulants, Whatever Happened to the PT and PTT?” and “Managing Trauma-induced Coagulopathy,” for the 2014 ASCLS-HI Clinical Laboratory Symposium Update at the Ko’olan Conference Center near Honolulu, Hawaii, October 21 and 22 (well, someone has to do it!). Times for George’s talks are to be announced. We hope you can attend. Go to ASCLS-HI and click on 2014 ASCLS-HI Clinical Laboratory Symposium Update.

Drawing Above Heparin Line

We avoid collecting blood from an arm that has an intravenous line, however this practice seems to rely on conventional wisdom, not data. Here is a question from Dennis Ernst, Center for Phlebotomy Education about collecting above a heparin line:

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Euglobulin Lysis Time

From friend and colleague Cassandra McGeachy, Louisiana Coagulation Laboratory,

Hi George, I am looking for procedures available for performing the euglobulin lysis time (ELT). I am looking to update my present method if there are any options available.

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