From Jo-Ann Luy:
What percentage of specimens with pseudothrombocytopenia caused by EDTA-dependent platelet satellitosis is resolved by collecting in a sodium citrate tube?
Jo-Ann Luy
Satellite Laboratory Services
Redwood City, CA
Platelet Satellitosis
Dear Jo-Ann Luy, I’ve never seen data expressing a percentage, perhaps some of our participants have an answer. Platelet satellitosis in EDTA is relatively common, however, and in my experience it often appears in the sodium citrate tube, although the satellitosis may be less apparent than in the EDTA tube and the platelet count may be a little higher. I recommend whenever you find platelet satellitosis, collect both a sodium citrate and a heparin additive tube, it may be the phenomenon is less apparent in heparin than in the other two. Geo.
Dear Sir,
I would like to know is there any kit for VWD inhibitor study.
with regards, Vilas Hiremath.
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This ASCLS Scientific Session is scheduled for Thursday, July 29, 2-3 PM in the Anaheim Convention Center:
What’s new in antithrombotics? Everything. We now monitor antiplatelet drugs aspirin, clopidogrel, and in 2010, prasugrel. What do we do about fondaparinux, and the 2010 oral anticoagulants rivaroxaban and dabigatran? And we still don’t know how to monitor direct thrombin inhibitors. Are chromogenic X and chromogenic anti-Xa the answer?
Objectives:
- Brief summary of current antithrombotic practice
- Monitor antiplatelet drugs, fondaparinux, direct thrombin inhibitors, and 2010 oral anticoagulants
- Employ chromogenic X and chromogenic anti-Xa to monitor several new anticoagulants.
Here is the handout for this presentation:
The following poster will be presented Thursday, July 29, 2-5 PM at the AACC annual meeting:
p2y12-receptor-blockade
If you have any posters or platform presentations you would like me to post here, please send an e-mail to george@fritsmafactor.com. Thank you.
Here are the handouts for the remaining two lectures provided by Margaret Fritsma, MA MT (ASCP) SBB and me at the VI Congreso Nacional de Microbiologia, 29-30 de Junio y 1 de Julio de 2010 in Tegucigalpa, Honduras. The first two lecture handouts were posted on July 15, 2010. Today’s additional presentation handouts are Administracion de Sangre: Mejorar la practica Transfusional, Disminuir Costos!, and Terapia para Hemofilia; Desde Rasputin a los Recombinantes. I also want to acknowledge our translator, Maria “Auxi” Valladares, and again our kind hostess, Dra Milena Vanegas, MSc. The handouts are provided en Espanol and in English:
Here is a message from Bill Pierce in Denver. I had the pleasure of working with Bill at Esoterix Coagulation a few years ago, and have stayed in touch with him since. He is now the manager of www.bplaboratoryconsulting.com. Bill has also served on the board of the Colorado Association for Continuing Medical Laboratory Education (CACMLE), the folks who accredit our audio modules. CACMLE has a cool new web site, http://www.cacmle.org.
Hi George, I hope all is well with you and your family.
I need a written procedure for testing centrifuge for platelet poor plasma. I also need a procedure for how long can a citrated specimen set before it is centrifuged? Does the spun citrated sample need to be refrigerated after it is centrifuged or can it set at room temperature before running the sample? How soon do you need to freeze a citrated sample? One last question: before a provider orders a complete expensive thrombotic risk profile would it be appropriate to have the physician order a PT and PTT first or should they just order the profile?
Regards, Bill
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Hi, This is my first time using this website and I have to say that it looks very helpful. I’m moving to the Innovance D-dimer (Siemens) and need to do a new normal range study. I was going to purchase a normal donor set from Precision BioLogic but they told me that they do not provide a set for normal range for D-dimer because this normal range should be done from fresh specimens and their products are frozen pheresis samples. My question, is it true that the normal range for the D-dimer must be done from fresh specimens? If not, where can I get a normal donor set to run my study?
Thank you,
Yexenia López, MT (ASCP)
Cambridge Hospital, Cambridge, MA
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From Dr. Larry Brace at Edward Hospital in Naperville, IL:
George, I know you get asked about this on Fritsma Factor. Can you point me to a good study on minimum volumes for various coag tube sizes? I know it is out there, but can’t find it at the moment–I don’t want to recreate the wheel. I think Dave did one. Also, one of the medical centers I consult for wants to switch to plastic tubes and wants to know how to validate.
Larry D. Brace, Ph.D., MT(ASCP)SH
Scientific Director of Laboratories
Edward Hospital, Naperville, IL
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Specimen Collection | GeorgeFritsma | 
July 25, 2010 2:11 pm | 
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