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Global Hemostasis Assays

Thromboelastography and Thrombin Generation

Thromboelastograph

> Saturday, May-16-2009
Kim Kinney at Clarian has this question about the Thromboelastograph:

A  pathologist who trained here asked me about the thromboelastograph (TEG).  Do you have any information on who uses this device, how difficult it is to perform, and QC?  We have had several docs asking us to get this device but we have not gone there yet!  Is it more of a POC device?  Thanks.

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Hepsorb and Heparinase

> Wednesday, February-04-2009
Last August, Julie Schartiger asked a question about mixing studies, and I provided a summary based on the algorithm we use at University of Alabama at Birmingham. I referred to Hepsorb, a reagent we use to neutralize therapeutic heparin in specimens for mixing studies. Stephen Duff of Precision BioLogic has asked me to define and describe Hepsorb.
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Bleeding Time Test

> Friday, April-25-2008

From Andrea Harper:

We continue to offer bleeding time testing. I would like to offer our pathologists an alternative to replace this ancient testing. In a lecture that you gave in October, 2007 in Portland, Maine, you spoke of the PFA-100. We are a 25 bed critical access facility. I'm not sure if it would be cost effective to purchase this device. We only perform 10 BT's per year. Is this a tests that can be sent out to a reference lab? I would appreciate any assistance you would give. Thank you, Andrea

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Clot Retraction

> Tuesday, January-29-2008
I thought the clot retraction test had disappeared when the earth cooled, but I heard from Maggie Schneider MT (ASCP) and Karri Henderson MT (ASCP) at William Beaumont Hospital in Oakland, MI, who occasionally use it. If an institution as "august" as Beaumont is using the clot retraction test, there must be more folks in North America using it. So I went to the books, specifically one Donna Corriveau and I edited and published in 1988.
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Global Assays: Calibrated Automated Thrombogram (CAT)

> Tuesday, January-08-2008
I meant to mention in a previous post Stago-US is marketing a global hemostasis system called the Calibrated Automated Thrombogram (CAT) from Thermo Electron Corp. And another called ROTEM. I saw one of the CATs at the ASH meeting in Atlanta this past December...
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Thromboelastography

> Wednesday, December-26-2007

Jerry Sapp, Blood Bank Supervisor at Birmingham's respected Children's Hospital of Alabama asks whether Thromboelastography would be of any use in monitoring the coagulopathy associated with massive transfusion.

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